Colonel John Pickering, baptised 3 December 1615, died 24 November 1645, was a member of the landed gentry from Northamptonshire who served with the Parliamentarian army in the First English Civil War. Like his elder brother Sir Gilbert Pickering, a close ally of Oliver Cromwell, he was a religious Independent, known for his devout faith and radical views. Appointed colonel of an infantry regiment in the New Model Army, he died of fever at Ottery St Mary on 24 November 1645.