The portal-visceral hypothesis describes a possible mechanism for some of the health effects of obesity, particularly the metabolic syndrome. It says that obesity (especially visceral obesity) results in increased circulation of free fatty acids and thus, via Randle's effect, in insulin resistance. The word "portal" refers to the hepatic portal circulation from the digestive system to the liver. The portal-visceral hypothesis is a replacement for the earlier "portal hypothesis", which said that visceral obesity leads to an increase in fatty acid levels specifically in the portal vein.
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| - النظرية البوابية (ar)
- Portal hypothesis (en)
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| - النظرية البوابية (بالإنجليزية: Portal hypothesis) هي نظرية تصف الآلية المحتملة لبعض الآثار الصحية للسمنة، وخاصة متلازمة التمثيل الغذائي. تنص النظربة على أن زيادة الأحماض الدهنية الحرة في الدم تلعب دوراً في مقاومة الخلايا للأنسولين. تشير كلمة «بوابية» إلى الدورة الدموية البابية الكبدية التي تحمل نواتج الأمتصاص من الجهاز الهضمي إلى الكبد. (ar)
- The portal-visceral hypothesis describes a possible mechanism for some of the health effects of obesity, particularly the metabolic syndrome. It says that obesity (especially visceral obesity) results in increased circulation of free fatty acids and thus, via Randle's effect, in insulin resistance. The word "portal" refers to the hepatic portal circulation from the digestive system to the liver. The portal-visceral hypothesis is a replacement for the earlier "portal hypothesis", which said that visceral obesity leads to an increase in fatty acid levels specifically in the portal vein. (en)
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| - النظرية البوابية (بالإنجليزية: Portal hypothesis) هي نظرية تصف الآلية المحتملة لبعض الآثار الصحية للسمنة، وخاصة متلازمة التمثيل الغذائي. تنص النظربة على أن زيادة الأحماض الدهنية الحرة في الدم تلعب دوراً في مقاومة الخلايا للأنسولين. تشير كلمة «بوابية» إلى الدورة الدموية البابية الكبدية التي تحمل نواتج الأمتصاص من الجهاز الهضمي إلى الكبد. (ar)
- The portal-visceral hypothesis describes a possible mechanism for some of the health effects of obesity, particularly the metabolic syndrome. It says that obesity (especially visceral obesity) results in increased circulation of free fatty acids and thus, via Randle's effect, in insulin resistance. The word "portal" refers to the hepatic portal circulation from the digestive system to the liver. The portal-visceral hypothesis is a replacement for the earlier "portal hypothesis", which said that visceral obesity leads to an increase in fatty acid levels specifically in the portal vein. (en)
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