Poughkeepsie Meeting House (Hooker Avenue) is a historic Quaker (Society of Friends) meeting house at 249 Hooker Avenue in Poughkeepsie, New York. It was built in 1927, and is a two-story, rectangular, Colonial Revival style brick building, with a basement. It has a gable roof and projecting entrance pavilion. It was listed on the National Register of Historic Places in 1989.