The 2010 TUMS Fast Relief 500 was a NASCAR Sprint Cup Series stock car race that was held on October 24, 2010, at Martinsville Speedway in Martinsville, Virginia. It was contested over 500 laps, and was the thirty-second race of the season and the sixth race in the season-ending Chase for the Sprint Cup for the 2010 NASCAR Sprint Cup Series. The race was won by Denny Hamlin for the Joe Gibbs Racing team. Mark Martin driving for Hendrick Motorsports finished second and Richard Childress Racing's Kevin Harvick , who started thirty-sixth, came third.