The 2021–22 Southern Football League season was the 119th in the history of the Southern League since its establishment in 1894. The league had two Premier divisions (Central and South) at Step 3 of the National League System (NLS) and two Division One divisions (Central and South) at Step 4. These correspond to levels 7 and 8 of the English football league system. The allocations for Step 4 this season were announced by The Football Association (FA) on 17 May 2021.