Local elections were held in the province of Isabela on May 9, 2022, as part of the 2022 Philippine general election. Voters selected candidates for all local positions: a mayor, vice-mayor and councilors, as well as members of the Sangguniang Panlalawigan, the governor, vice-governor and for the six districts of Isabela for board members and congress. The province of Isabela is considered by Comelec as one of the vote-rich provinces in the Philippines for having 1,112,858 voters in the 2022 national and local elections.