α5β1, also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It is composed of α5 (ITGA5/CD49e) and β1 (ITGB1/CD29) subunits. It is the primary receptor for fibronectin. The interaction of VLA-5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes (From the Cell Migration Gateway ITGA5 ITGB1). α5β1-integrin is transported inside the cell by the kinesin KIF1C, a kinesin-3 organelle transporter that walks along microtubules.
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rdfs:label
| - Alpha-5 beta-1 (en)
- VLA-5 (ru)
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| - α5β1, also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It is composed of α5 (ITGA5/CD49e) and β1 (ITGB1/CD29) subunits. It is the primary receptor for fibronectin. The interaction of VLA-5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes (From the Cell Migration Gateway ITGA5 ITGB1). α5β1-integrin is transported inside the cell by the kinesin KIF1C, a kinesin-3 organelle transporter that walks along microtubules. (en)
- VLA-5 (англ. Very Late Antigen-5; интегрин α5β1) — мембранный белок, гетеродимерный интегрин подсемейства β1-интегринов (рецепторы VLA), состоящий из альфа цепи α5 (CD49e) и бета цепи β1 (CD29). Рецептор фибронектина, играет роль в клеточной миграции. (ru)
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| - α5β1, also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It is composed of α5 (ITGA5/CD49e) and β1 (ITGB1/CD29) subunits. It is the primary receptor for fibronectin. The interaction of VLA-5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes (From the Cell Migration Gateway ITGA5 ITGB1). α5β1-integrin is transported inside the cell by the kinesin KIF1C, a kinesin-3 organelle transporter that walks along microtubules. (en)
- VLA-5 (англ. Very Late Antigen-5; интегрин α5β1) — мембранный белок, гетеродимерный интегрин подсемейства β1-интегринов (рецепторы VLA), состоящий из альфа цепи α5 (CD49e) и бета цепи β1 (CD29). Рецептор фибронектина, играет роль в клеточной миграции. (ru)
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