William "Silent Bill" Hopke (November 2, 1881 – April 18, 1959) was an American professional baseball infielder. He played in the minor leagues from 1902 to 1914 with several teams. Hopke also played in the 1909 American Series for the Detroit Tigers, though he never played in a major league game for Detroit. He also played for the Almendares club in the Cuban League in 1911.