German submarine U-165 was a Type IXC U-boat of Nazi Germany's Kriegsmarine built for service during World War II. The keel for this boat was laid down on 30 August 1940 at the Deutsche Schiff- und Maschinenbau AG, Bremen yard as yard number 704. She was launched on 15 August 1941 and commissioned on 3 February 1942 under the command of Fregattenkapitän Eberhard Hoffmann. An RAF aircraft with a Czechoslovak crew sank her on 27 September 1942.