Holmes Run Acres is a community of 355 houses in Fairfax County, Virginia, in the Washington, D.C. suburbs. Nearly all of the neighborhood is within the Holmes Run Acres Historic District, listed on the National Register of Historic Places. The first Fairfax County subdivision designed by architects Nicholas Satterlee and Francis D. Lethbridge, Holmes Run Acres influenced the architecture and site planning at nearby Pine Spring and elsewhere, including the Potomac Overlook and Carderock Springs historic districts in Montgomery County, Maryland.