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Medetomidine is a synthetic drug used as both a surgical anesthetic and analgesic. It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid. It is an α2 adrenergic agonist that can be administered as an intravenous drug solution with sterile water.

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  • Medetomidin (de)
  • Médétomidine (fr)
  • Medetomidina (it)
  • Medetomidine (en)
  • メデトミジン (ja)
  • Medetomidine (nl)
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  • Medetomidin ist eine chemische Verbindung aus der Gruppe der Imidazole, die in der Tier- und Humanmedizin als Sedativum und Schmerzmittel eingesetzt wird. Das pharmakologisch wirksame Enantiomer im Racemat [1:1-Gemisch der (R)-Form und der (S)-Form] ist die (R)-(+)-Form. Das Racemat wird vor allem als wasserlösliches, weißes, kristallines Medetomidin·Hydrochlorid verwendet. (de)
  • La médétomidine est un α2-agoniste utilisé en anesthésiologie vétérinaire. Il est l'un des sédatifs les plus puissants de sa classe. (fr)
  • メデトミジン(英:medetomidine)とはα2アドレナリン受容体作動薬の1つ。α2受容体を活性化することにより鎮静作用、鎮痛作用、筋弛緩作用を示す。副作用として心臓の刺激伝導系の遮断による徐脈、一過性の血圧上昇に続発する心拍出量と血圧の低下を引き起こす。フィンランドのオリオン社が開発した。商品名はドミトール(Domitor、製造元はオリオン社、国内販売元は日本全薬工業)。アチパメゾールが拮抗的にメデトミジンの作用を抑制する。 船舶向け防汚塗料の有効成分としても使われている。 (ja)
  • Medetomidine is een in de veterinaire anesthesiologie zeer vaak gebruikte α2-agonist. Het is een van de meest krachtige sedativa uit deze groep. (nl)
  • La medetomidina è un potentissimo agonista selettivo alfa2-adrenergico. In medicina veterinaria ne è consentito l'uso solo nel cane e nel gatto. Viene associato alla ketamina per indurre un'anestesia di breve durata. (it)
  • Medetomidine is a synthetic drug used as both a surgical anesthetic and analgesic. It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid. It is an α2 adrenergic agonist that can be administered as an intravenous drug solution with sterile water. (en)
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