About: 2,2'-Azobis(2-amidinopropane) dihydrochloride

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2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH) is a chemical compound used to study the chemistry of the oxidation of drugs. It is a free radical-generating azo compound. It is gaining prominence as a model oxidant in small molecule and protein therapeutics for its ability to initiate oxidation reactions via both nucleophilic and free radical mechanisms.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Chemical compound yago:WikicatAzoCompounds yago:WikicatMolecularFormulas yago:Abstraction100002137 yago:Cognition100023271 yago:Communication100033020 yago:Compound105870180 yago:Concept105835747 yago:Content105809192 yago:Formula106816935 yago:Idea105833840 yago:Message106598915 yago:MolecularFormula106817173 yago:PsychologicalFeature100023100 chemical compound yago:Statement106722453 yago:Whole105869584
rdfs:label	2,2'-Azobis(2-amidinopropane) dihydrochloride (en) 2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드 (ko)
rdfs:comment	2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드(영어: 2,2'-azobis(2-amidinopropane) dihydrochloride, AAPH)는 약물의 산화에 대해 연구하는 데 사용되는 화합물이다. 2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드는 자유 라디칼을 생성하는 아조 화합물이다. 2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드는 친핵성 및 자유 라디칼 메커니즘을 통해 산화 반응을 개시할 수 있는 능력으로 인해 저분자 및 단백질 치료제에서 산화제로 주목받고 있다. 2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드는 의 이원 혼합물의 상이한 조합으로 유도 산화된 리놀레산에 대한 실험에서 사용되었다. 실험에 따르면 일부 이원 혼합물은 상승적 항산화 효과를 유발할 수 있지만, 다른 혼합물은 길항 작용을 유발할 수 있다는 것을 보여준다. (ko) 2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH) is a chemical compound used to study the chemistry of the oxidation of drugs. It is a free radical-generating azo compound. It is gaining prominence as a model oxidant in small molecule and protein therapeutics for its ability to initiate oxidation reactions via both nucleophilic and free radical mechanisms. (en)
foaf:depiction
dcterms:subject	Amidines Azo compounds
Wikipage page ID	35625740 (xsd:integer)
Wikipage revision ID	1061072159 (xsd:integer)
Link from a Wikipage to another Wikipage	Antagonism (chemistry) Amidines Azo compounds Small molecule dbr:Linoleic_acid Synergy Drug Protein Azo compound Free radical Oxidation Natural phenol Antioxidant effect of natural phenols
sameAs	2,2'-Azobis(2-amidinopropane) dihydrochloride 2,2'-Azobis(2-amidinopropane) dihydrochloride 2,2'-Azobis(2-amidinopropane) dihydrochloride 2,2'-Azobis(2-amidinopropane) dihydrochloride 2,2'-Azobis(2-amidinopropane) dihydrochloride 2,2'-Azobis(2-amidinopropane) dihydrochloride 2,2'-Azobis(2-amidinopropane) dihydrochloride
dbp:wikiPageUsesTemplate	dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Cascite dbt:Fdacite
thumbnail	wiki-commons:Special:FilePath/2,2'-Azobis(2-amidinopropane)_dihydrochloride.svg?width=300
ImageFile	22 (xsd:integer)
IUPACName	-22 (xsd:integer)
OtherNames	AAPH; 2,2'-Azobisisobutyramidinium chloride (en)
has abstract	2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH) is a chemical compound used to study the chemistry of the oxidation of drugs. It is a free radical-generating azo compound. It is gaining prominence as a model oxidant in small molecule and protein therapeutics for its ability to initiate oxidation reactions via both nucleophilic and free radical mechanisms. 2,2′-azobis (2-amidinopropane) dihydrochloride has been used in experiments on linoleic acid subjected to induced oxidation with different combinations of binary mixtures of natural phenolics. The experiments show that some binary mixtures can lead to a synergetic antioxidant effect while other mixtures lead to an antagonistic effect. (en) 2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드(영어: 2,2'-azobis(2-amidinopropane) dihydrochloride, AAPH)는 약물의 산화에 대해 연구하는 데 사용되는 화합물이다. 2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드는 자유 라디칼을 생성하는 아조 화합물이다. 2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드는 친핵성 및 자유 라디칼 메커니즘을 통해 산화 반응을 개시할 수 있는 능력으로 인해 저분자 및 단백질 치료제에서 산화제로 주목받고 있다. 2,2'-아조비스(2-아미디노프로페인) 다이하이드로클로라이드는 의 이원 혼합물의 상이한 조합으로 유도 산화된 리놀레산에 대한 실험에서 사용되었다. 실험에 따르면 일부 이원 혼합물은 상승적 항산화 효과를 유발할 수 있지만, 다른 혼합물은 길항 작용을 유발할 수 있다는 것을 보여준다. (ko)
gold:hypernym	Compound
prov:wasDerivedFrom	wikipedia-en:2,2'-Azobis(2-amidinopropane)_dihydrochloride?oldid=1061072159&ns=0
page length (characters) of wiki page	3067 (xsd:nonNegativeInteger)
alternative name	AAPH; 2,2'-Azobisisobutyramidinium chloride (en)
IUPAC name	(1Z,1'Z)-2,2'-[(E)-1,2-Diazenediyl]bis(2-methylpropanimidamide) dihydrochloride (en)
foaf:isPrimaryTopicOf	wikipedia-en:2,2'-Azobis(2-amidinopropane)_dihydrochloride
is Link from a Wikipage to another Wikipage of	C8H20Cl2N6 2,2'-azobis(2-amidinopropane) dihydrochloride Dichlorofluorescein Naturally occurring phenols 2,2'-Azobisisobutyramidinium chloride 2,2′-azobis (2-amidinopropane) dihydrochloride AAPH
is Wikipage redirect of	C8H20Cl2N6 2,2'-azobis(2-amidinopropane) dihydrochloride 2,2'-Azobisisobutyramidinium chloride 2,2′-azobis (2-amidinopropane) dihydrochloride AAPH
is foaf:primaryTopic of	wikipedia-en:2,2'-Azobis(2-amidinopropane)_dihydrochloride

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