The 2017–18 Southern Jaguars basketball team represented Southern University during the 2017–18 NCAA Division I men's basketball season. The Jaguars, led by interim head coach , played their home games at the F. G. Clark Center in Baton Rouge, Louisiana as members of the Southwestern Athletic Conference. They finished the season 15–18, 10–8 in SWAC play to finish in fifth place. Due to Grambling State's Academic Progress Rate violations and subsequent postseason ineligibility, the Jaguars received the No. 4 seed in the SWAC tournament. They defeated Jackson State in the quarterfinals before losing to Arkansas–Pine Bluff in the semifinals.