The 2018–19 Florida Gulf Coast Eagles women's basketball team will represent Florida Gulf Coast University during the 2018–19 NCAA Division I women's basketball season. The Eagles, led by seventeenth year head coach Karl Smesko, will play their home games at the Alico Arena and were members of the Atlantic Sun Conference. They finish the season 28–4, 16–0 in A-Sun play to win the Atlantic Sun regular season. Florida Gulf Coast won the championship game over Liberty, 72–49. They lost in the first round to Miami (FL).