The 2018 UAB Blazers football team represented the University of Alabama at Birmingham (UAB) in the 2018 NCAA Division I FBS football season as a member of the West Division of Conference USA (C-USA). They were led by third-year head coach Bill Clark and played their home games at Legion Field in Birmingham, Alabama. They finished the season 11–3, 7–1 in C-USA play to be champions of the West Division. They represented the West Division in the C-USA Championship Game where they defeated Middle Tennessee to win their first ever C-USA championship. They were invited to the Boca Raton Bowl where they defeated Northern Illinois to claim their first bowl win in program history.