The 2021 Arizona Wildcats baseball team represented the University of Arizona during the 2021 NCAA Division I baseball season. The Wildcats played their home games for the 10th season at Hi Corbett Field. The team was coached by Jay Johnson in his 6th season and final season at Arizona. Following the season, Coach Johnson was hired as the head baseball coach at Louisiana State University. The Wildcats ranked 10th in Collegiate Baseball's preseason poll - their highest preseason ranking in any poll since 2013 - and their incoming recruiting class was ranked 4th in the nation by D1Baseball. On May 23, the Wildcats clinched at least a share of the Pac-12 Championship for the first time since the 2012 season that saw the team win the College World Series. Following a 3-11 loss by the Oregon Du