The 2021 NCAA Division I women's basketball tournament was a single-elimination tournament of 64 teams to determine the National Collegiate Athletic Association (NCAA) Division I college basketball national champion for the 2020–21 NCAA Division I women's basketball season. The 39th edition of the tournament began on March 21, 2021, in sites around San Antonio, Texas, and concluded with the championship game on April 4 at the Alamodome, with the Stanford Cardinal defeating the Arizona Wildcats 54–53 to win their third NCAA title.