The 2021 Washington State Cougars football team represented Washington State University during the 2021 NCAA Division I FBS football season. They were led by second-year head coach Nick Rolovich in the first 7 games; Rolovich was fired on October 18 after refusing to comply with Washington's COVID-19 vaccination mandate. Defensive Coordinator Jake Dickert took over as the team's interim head coach for the reminder of the season. He was announced as the Cougars 34th head coach following their Apple Cup victory on November. The team played their home games in Martin Stadium in Pullman, Washington, and competed as members of the North Division of the Pac-12 Conference.