The 2022 Interwetten European Darts Open was the fifth of thirteen PDC European Tour events on the 2022 PDC Pro Tour. The tournament took place at the Ostermann-Arena, Leverkusen, Germany, from 6–8 May 2022. It featured a field of 48 players and £140,000 in prize money, with £25,000 going to the winner. Michael van Gerwen entered the event as defending champion, having defeated Rob Cross 8–6 in the 2019 final. He successfully defended his title with an 8–5 win over Dimitri Van den Bergh in the final.