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5-EAPB (1-(benzofuran-5-yl)-N-ethylpropan-2-amine) is a potentially entactogenic amphetamine which is structurally related to 5-MAPB and 5-APB. It might be predicted to show similar effects to these drugs in humans, but the pharmacology of 5-EAPB remains unstudied as of 2020. 5-EAPB is similar in structure to compounds such as 5-APB which are claimed to be agonists of the 5-HT2C receptor as well as a triple monoamine reuptake inhibitor, however 5-EAPB is not listed as an example in this patent, and it is not yet established to what extent the activity of 5-EAPB resembles that of 5-APB.

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  • 5-EAPB (en)
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  • 5-EAPB (1-(benzofuran-5-yl)-N-ethylpropan-2-amine) is a potentially entactogenic amphetamine which is structurally related to 5-MAPB and 5-APB. It might be predicted to show similar effects to these drugs in humans, but the pharmacology of 5-EAPB remains unstudied as of 2020. 5-EAPB is similar in structure to compounds such as 5-APB which are claimed to be agonists of the 5-HT2C receptor as well as a triple monoamine reuptake inhibitor, however 5-EAPB is not listed as an example in this patent, and it is not yet established to what extent the activity of 5-EAPB resembles that of 5-APB. (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/5-EAPB_Structure.svg
  • http://commons.wikimedia.org/wiki/Special:FilePath/5-EAPB_molecule_ball.png
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  • Ball-and-stick model of 5-EAPB molecule (en)
ATC prefix
  • none (en)
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legal DE
  • NpSG (en)
legal UK
  • Class B (en)
molecular weight
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O
pregnancy category
  • ? (en)
SMILES
  • CCCC1=CC=C2C=C1 (en)
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StdInChIKey
  • ZBZDDOARNPAMSP-UHFFFAOYSA-N (en)
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has abstract
  • 5-EAPB (1-(benzofuran-5-yl)-N-ethylpropan-2-amine) is a potentially entactogenic amphetamine which is structurally related to 5-MAPB and 5-APB. It might be predicted to show similar effects to these drugs in humans, but the pharmacology of 5-EAPB remains unstudied as of 2020. 5-EAPB is similar in structure to compounds such as 5-APB which are claimed to be agonists of the 5-HT2C receptor as well as a triple monoamine reuptake inhibitor, however 5-EAPB is not listed as an example in this patent, and it is not yet established to what extent the activity of 5-EAPB resembles that of 5-APB. (en)
legal CA
  • Schedule I (en)
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CAS number
  • 1445566-01-7
FDA UNII code
  • 889D8VM2SL
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