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About: 6-Formylindolo(3,2-b)carbazole     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : dbo:ChemicalCompound, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundchemical compound New Facet based on Instances of this Class

6-Formylindolo[3,2-b]carbazole (FICZ) is a chemical compound with the molecular formula C19H12N2O. It is a nitrogen heterocycle, having an extremely high affinity (Kd = 7 x 10−11M) for binding to the aryl hydrocarbon receptor (AHR). It was originally identified as a photooxidized derivative of the amino acid tryptophan and suggested to be the endogenous ligand of the AHR. Later, also enzymatic formation of FICZ was shown.