The Afghanistan cricket team toured Bangladesh in September and October 2016 to play three One Day Internationals (ODIs) matches. This was Afghanistan's first full series against a Test-playing side other than Zimbabwe and was the first bilateral series between the two sides. It was also Bangladesh's first home bilateral ODI series against an Associate Nation since Ireland toured in 2008. Ahead of the ODI series there was a fifty-over warm-up game between the Bangladesh Cricket Board XI and Afghanistan in Fatullah.