State Route 168 (SR 168) is an east-west state highway in the U.S. state of California that is separated into two distinct segments by the Sierra Nevada mountains. The western segment runs from State Routes 41 and 180 in Fresno east to Huntington Lake along the western slope of the Sierra. The eastern segment connects Lake Sabrina in the Eastern Sierra to State Route 266 in the community of Oasis, just to the west of the Nevada border. The eastern segment of SR 168 also forms a concurrency with U.S. Route 395 between Bishop and Big Pine.