The Cumberland Subdivision is a railroad line owned and operated by CSX Transportation in the U.S. states of Maryland and West Virginia. The line runs from Brunswick, Maryland, west to Cumberland, Maryland, along the old Baltimore and Ohio Rail Road (B&O) main line. At its east end, the Cumberland Subdivision becomes the Metropolitan Subdivision; at its west end at Cumberland, Maryland it becomes the Cumberland Terminal Subdivision. It meets the Shenandoah Subdivision at Harpers Ferry, West Virginia, and the Lurgan Subdivision at Cherry Run, West Virginia.