David E. Smith (born 1939) is an American medical doctor from the United States specializing in addiction medicine, the psycho-pharmacology of drugs, new research strategies in the management of drug abuse problems, and proper prescribing practices for physicians. He is the Founder of the Haight Ashbury Free Clinics of San Francisco, a Fellow and Past President of the American Society of Addiction Medicine, Past President of the California Society of Addiction Medicine, Past Medical Director for the California State Department of Alcohol and Drug Programs, Past Medical Director for the California Collaborative Center for Substance Abuse Policy Research, and former adviser to the Betty Ford Center.