Debra J. Heffernan (born April 8, 1962) is an American politician. She is a Democratic member of the Delaware House of Representatives, representing District 6. Heffernan earned her BS in biology from the University of Delaware and her MS in environmental toxicology from Duke University. Heffernan is apart of the centrist wing of the Democratic Party. She supported centrist US Senator Tom Carper in the 2018 US Senate election in Delaware over progressive challenger Kerri Evelyn Harris. In 2022, she defeated progressive challenger Becca Cotto in the Democratic primary.