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Drosophila C virus belongs to the genus Cripavirus and was previously thought to be a member of the virus family Picornaviridae; it has since been classified as belonging to the Dicistroviridae. It is a single stranded positive sense RNA virus of approximately 9300 nucleotides and it contains two open reading frames. The virus particles are 30 nm in diameter and are made up of approximately 30% of RNA and 70% protein. The virus capsid is composed of three major polypeptides and two minor polypeptides.

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  • Drosophila C virus (es)
  • Drosophila C virus (en)
  • Drosophila C virus (fr)
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  • Drosophila C virus belongs to the genus Cripavirus and was previously thought to be a member of the virus family Picornaviridae; it has since been classified as belonging to the Dicistroviridae. It is a single stranded positive sense RNA virus of approximately 9300 nucleotides and it contains two open reading frames. The virus particles are 30 nm in diameter and are made up of approximately 30% of RNA and 70% protein. The virus capsid is composed of three major polypeptides and two minor polypeptides. (en)
  • Drosophila C virus es una especie de virus perteneciente al género y se pensaba previamente que era un miembro de la familia Picornaviridae; desde entonces se ha clasificado en la familia Dicistroviridae.​ Es un virus de cadena sencilla de ARN con sentido positivo, con un genoma de aproximadamente 9300 nucleótidos y contiene dos marcos abiertos de lectura.​ Las partículas víricas tienen un diámetro de 30 nm y están constituidos por aproximadamente un 30% de ARN y un 70% de proteína.​ La cápside viral está compuesta por tres polipeptidos principales y dos menores.​ Drosophila C virus infecta a Drosophila melanogaster y fue descubierta por primera vez a principios de los años 1970 en una cepa francesa de Drosophila.​ El virus se transmite mediante la alimentación, de modo que prácticamente (es)
  • Le virus C de la drosophila (DCV) est un virus, de 25 à 30 nm de diamètre, appartenant au groupe des Picornaviridae. Le nom du virus vient de la première lettre du village de Charolles, situé en France, où le virus a été isolé pour la première fois en laboratoire chez une souche de Drosophila melanogaster. Ce virus infecte naturellement le genre Drosophila au stade larvaire par contact ou par ingestion de nourriture contaminée. Il ne se transmet pas de manière héréditaire, mais horizontalement. (fr)
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  • Cripavirus (en)
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  • Drosophila'' C virus (en)
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  • Drosophila C virus belongs to the genus Cripavirus and was previously thought to be a member of the virus family Picornaviridae; it has since been classified as belonging to the Dicistroviridae. It is a single stranded positive sense RNA virus of approximately 9300 nucleotides and it contains two open reading frames. The virus particles are 30 nm in diameter and are made up of approximately 30% of RNA and 70% protein. The virus capsid is composed of three major polypeptides and two minor polypeptides. Drosophila C virus was first discovered in the early 1970s in a French strain of Drosophila melanogaster, but can also infect other Drosophila species in laboratory settings. The virus is transmitted by feeding and affects survival. However, experimental evidence has shown that when injected into adult flies the virus is pathogenic as it causes the adult flies to die within 3–4 days. Antiviral RNAi has been shown to be an important host defence against DCV, and DCV encodes a viral suppressor of RNAi that sequesters double-stranded RNA to prevent antiviral RNAi targeting the virus. Drosophila that are infected with Drosophila C virus develop more quickly, the females have a greater number of ovarioles than uninfected flies. Whilst based on this evidence it has been suggested DCV is a beneficial virus, this ignores the fact that the virus kills flies in only a few days (so total fitness in infected flies is still reduced), and any changes in development time or ovariole number likely represent a host life history shift (parasite-induced fecundity compensation). Further support for host fecundity compensation following DCV infection comes from work showing that this response varies with fly genetic background, with some fly lines showing increased fecundity following infection, while others show a fecundity reduction. Infection with Drosophila C virus can also increase the mortality rate within a Drosophila population. (en)
  • Drosophila C virus es una especie de virus perteneciente al género y se pensaba previamente que era un miembro de la familia Picornaviridae; desde entonces se ha clasificado en la familia Dicistroviridae.​ Es un virus de cadena sencilla de ARN con sentido positivo, con un genoma de aproximadamente 9300 nucleótidos y contiene dos marcos abiertos de lectura.​ Las partículas víricas tienen un diámetro de 30 nm y están constituidos por aproximadamente un 30% de ARN y un 70% de proteína.​ La cápside viral está compuesta por tres polipeptidos principales y dos menores.​ Drosophila C virus infecta a Drosophila melanogaster y fue descubierta por primera vez a principios de los años 1970 en una cepa francesa de Drosophila.​ El virus se transmite mediante la alimentación, de modo que prácticamente es no patogénico. Sin embargo, la evidencia experimental ha mostrado que cuando se inyecta en moscas adultas el virus es increíblemente patogénico, puesto que produce la muerte de las moscas adultas en el plazo de 3-4 días tras la inyección.​ Cuando se infecta a Drosophila con el Drosophila C virus, el insecto se desarrolla más rápido, las hembras son más pesadas y producen más huevos, por tanto se produce más descendencia en comparación con los individuos no infectados.​ La infección con el drosophila C virus también puede incrementar la tasa de mortalidad en una población de drosophila.​ (es)
  • Le virus C de la drosophila (DCV) est un virus, de 25 à 30 nm de diamètre, appartenant au groupe des Picornaviridae. Le nom du virus vient de la première lettre du village de Charolles, situé en France, où le virus a été isolé pour la première fois en laboratoire chez une souche de Drosophila melanogaster. Ce virus infecte naturellement le genre Drosophila au stade larvaire par contact ou par ingestion de nourriture contaminée. Il ne se transmet pas de manière héréditaire, mais horizontalement. Aucun symptôme particulier n'est visible. Néanmoins, l'infection virale impacte son hôte à ses différents stades de vie : un raccourcissement de la durée de développement de l'œuf à l'imago, une augmentation de la masse corporelle des femelles et de leurs capacités reproductives, une réduction du taux de survie larve-nymphale, ainsi qu'une modification de l'expression génétique de l'hôte avantageant ce dernier en augmentant sa valeur sélective. (fr)
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