Gabriel Pleydell (fl. 1519 – c.1591) of Midg Hall in the parish of Lydiard St John (later Lydiard Tregoze) in Wiltshire, was an English landowner and politician who served as Member of Parliament for the Wootton Bassett and Marlborough constituencies in the Parliament of England. Pleydell was born before 1519 into a large, affluent family. He entered politics in March 1553 as a member for Wootton Bassett, close to his family estate at Midgehall in Wiltshire. Pleydell's election to the Marlborough constituency two years later may have been made possible by his father's influential connections. He returned to the Wootton Bassett seat at the request of Sir John Thynne in 1563; he had supported Thynne in a dispute over the Knighthood of the Shire in 1559.