George DeBaptiste (c. 1815 – February 22, 1875) was a prominent African-American conductor on the Underground Railroad in southern Indiana and Detroit, Michigan. Born free in Virginia, he moved as a young man to the free state of Indiana. In 1840, he served as valet and then White House steward for US President William Henry Harrison, who was from that state. In the 1830s and 1840s DeBaptiste was an active conductor in Madison, Indiana. Located along the Ohio River across from Kentucky, a slave state, this town was a destination for refugee slaves seeking escape from slavery.