State Route 25 (SR 25) is a state highway in the eastern part of the U.S. state of Georgia. It travels south-to-north near the Atlantic Ocean, serving the Brunswick and Savannah metropolitan areas on its path from the Florida state line at the St. Marys River to the South Carolina state line at the Little Back River, a channel of the Savannah River. Except for the northern part of the highway, from Savannah to Port Wentworth, it is concurrent with U.S. Route 17 (US 17) for its entire length.