Sir Henry Killigrew (c. 1528 – 1603) was a Cornish diplomat and an ambassador for the Kingdom of England in the sixteenth century. He was several times employed by Elizabeth I in Scottish affairs and served as one of the English appointees to the Council of State of the Netherlands in the United Provinces in 1586 and 1587–1589. He served as a Member of Parliament for Newport & Launceston in 1553, for Saltash in 1563, and for Truro in 1571–2.