The Higashi-Osaka Route (東大阪線, Higashi-Osaka-sen), signed as Route 13, is one of the tolled routes of the Hanshin Expressway system serving the Keihanshin area in Kansai, Japan. It travels in a west to east direction from the Chūō ward of Osaka, beginning at a junction with the Loop Route and Ōsakakō Route, to the Daini Hanna Road in the city of Higashiōsaka. The expressway has a total length of 12.5 kilometers (7.8 mi).