The Homesite of John O. Meusebach is located at Loyal Valley in Mason County, Texas, 21 miles (34 km) north of Fredericksburg and 18 miles (29 km) southeast of the city of Mason, on U.S. Highway 87 to right-of-way at the intersection of US 87 and RM 2242. Meusebach moved to the property in 1869, after a tornado destroyed his family home in Comal County.