Jesse Lawrence Barnes (August 26, 1892 – September 9, 1961) was an American pitcher in Major League Baseball. Barnes began his major league career in 1914 with the Boston Braves. In 1917, he led the National League with 21 losses. On October 2, 1917, he became the only NL pitcher to walk twice in one inning. In 1920 he had 20 wins, following with 15 wins in 1921 and two victories in the 1921 World Series against the New York Yankees. Then, on May 7, 1922, he hurled a no-hitter against the Phillies; Cy Williams was the only baserunner, who walked and was erased on a double play.