Dr. John Albert Musselman Karefa-Smart (17 June 1915 – 26 August 2010) was a Sierra Leonean politician, medical doctor and university professor. He served as the first Foreign Minister under Sierra Leone's first Prime Minister, Sir Milton Margai. He was an ordained Elder of the United Methodist Church. A medical doctor by profession, Karefa-Smart was one of the founding fathers of the Sierra Leone People's Party (SLPP) in 1951. He was one of Sir Milton Margai's closest political advisors and a close personal friend. From 1957 to 1964, Karefa-Smart was a from Tonkolili District.