John Ormsby (1720–1805) was a soldier in the French and Indian War, Pontiac's Rebellion, and the American Revolution, and among the first settlers of Pittsburgh, Pennsylvania. The son of the Anglo-Irish landed gentry, he emigrated from Ireland to the Thirteen Colonies in 1752. After Pontiac's Rebellion, he received a land grant from King George III, and established a homestead on the banks of the Monongahela River. He established extensive economic and merchant interests in Bedford, Pennsylvania, and at the head of the Ohio River.