Jusepe Gutierrez (also known as Joseph and usually called only by his given name),) (born c. 1572; fl. 1590s, death date unknown) was a Native Nahua guide and explorer. He was the only known survivor of the Umana and Leyba expedition to the Great Plains in 1594 or 1595. In 1599 he guided Vicente de Zaldivar and in 1601 Governor Juan de Oñate on expeditions to the plains.