Kettle Creek is a tributary of the West Branch Susquehanna River running through Tioga, Potter, and Clinton counties, in Pennsylvania. It is slightly less than 43 miles (69 km) long. Although many streams in the Kettle Creek watershed are considered "Class A Wild Trout streams" by the Pennsylvania Fish and Boat Commission, the lower reaches of the stream experience acid mine drainage. The upper reaches of the creek are considered to be very high-quality.