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About: Medium spiny neuron     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Whole100003553, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: yago:WikicatNeuronsyago:Cell100006484yago:LivingThing100004258yago:NerveCell105465567yago:Object100002684yago:PhysicalEntity100001930yago:SomaticCell105430628yago:Whole100003553 New Facet based on Instances of this Class

Medium spiny neurons (MSNs), also known as spiny projection neurons (SPNs), are a special type of GABAergic inhibitory cell representing 95% of neurons within the human striatum, a basal ganglia structure. Medium spiny neurons have two primary phenotypes (characteristic types): D1-type MSNs of the direct pathway and D2-type MSNs of the indirect pathway. Most striatal MSNs contain only D1-type or D2-type dopamine receptors, but a subpopulation of MSNs exhibit both phenotypes.