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A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of undetermined significance. Other terms for such a protein are monoclonal protein, M protein, M component, M spike, spike protein, or paraprotein. This proliferation of the myeloma protein has several deleterious effects on the body, including impaired immune function, abnormally high blood viscosity ("thickness" of the blood), and kidney damage.

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  • بروتين الورم النقيي (ar)
  • Paraproteina (it)
  • Myeloma protein (en)
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  • بروتين الورم النقيي أو بروتين الورم النقوي هو عبارة عن جسم مضاد غير طبيعي (جلوبيولين مناعي) أو -في أغلب الأحيان- جزء منه مثل سلسلة الجلوبيولين المناعي الخفيفة، يتم إنتاجه بشكل مفرط من خلال تكاثر أحادي النسيلة الغير طبيعي لخلايا البلازما عادةً في الورم النخاعي المتعدد، هناك مصطلحات أخرى لمثل هذا البروتين هي بروتين M أو مركب M أو حسكة M أو بروتين حسكة أو بارابروتين، تكاثر بروتين الورم النقيي له تأثيرات ضارة على الجسم، حيث يتسبب في ضعف وظائف المناعة ولزوجة الدم العالية («سمك» الدم)بشكل غير طبيعى واعتلال الكلى. (ar)
  • A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of undetermined significance. Other terms for such a protein are monoclonal protein, M protein, M component, M spike, spike protein, or paraprotein. This proliferation of the myeloma protein has several deleterious effects on the body, including impaired immune function, abnormally high blood viscosity ("thickness" of the blood), and kidney damage. (en)
  • Una proteina del mieloma è un frammento di immunoglobulina anormale, come una catena leggera di immunoglobuline, che è prodotta in eccesso da una proliferazione monoclonale anormale delle plasmacellule, tipicamente nel mieloma multiplo. Altri termini per denominare tale proteina sono: la proteina M, il componente M, il picco M, la proteina spike (da non confondere con la proteina Spike dei coronavirus ) o la paraproteina. Questa proliferazione della proteina del mieloma ha diversi effetti deleteri sul corpo, tra cui compromissione della funzione immunitaria, viscosità del sangue anormalmente elevata ("spessore" del sangue) e danno renale. (it)
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  • بروتين الورم النقيي أو بروتين الورم النقوي هو عبارة عن جسم مضاد غير طبيعي (جلوبيولين مناعي) أو -في أغلب الأحيان- جزء منه مثل سلسلة الجلوبيولين المناعي الخفيفة، يتم إنتاجه بشكل مفرط من خلال تكاثر أحادي النسيلة الغير طبيعي لخلايا البلازما عادةً في الورم النخاعي المتعدد، هناك مصطلحات أخرى لمثل هذا البروتين هي بروتين M أو مركب M أو حسكة M أو بروتين حسكة أو بارابروتين، تكاثر بروتين الورم النقيي له تأثيرات ضارة على الجسم، حيث يتسبب في ضعف وظائف المناعة ولزوجة الدم العالية («سمك» الدم)بشكل غير طبيعى واعتلال الكلى. (ar)
  • A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of undetermined significance. Other terms for such a protein are monoclonal protein, M protein, M component, M spike, spike protein, or paraprotein. This proliferation of the myeloma protein has several deleterious effects on the body, including impaired immune function, abnormally high blood viscosity ("thickness" of the blood), and kidney damage. (en)
  • Una proteina del mieloma è un frammento di immunoglobulina anormale, come una catena leggera di immunoglobuline, che è prodotta in eccesso da una proliferazione monoclonale anormale delle plasmacellule, tipicamente nel mieloma multiplo. Altri termini per denominare tale proteina sono: la proteina M, il componente M, il picco M, la proteina spike (da non confondere con la proteina Spike dei coronavirus ) o la paraproteina. Questa proliferazione della proteina del mieloma ha diversi effetti deleteri sul corpo, tra cui compromissione della funzione immunitaria, viscosità del sangue anormalmente elevata ("spessore" del sangue) e danno renale. (it)
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