Nathaniel Briggs Borden (April 15, 1801 – April 10, 1865) was a businessman and politician from Fall River, Massachusetts. He served as a U.S. Representative from Massachusetts's 10th congressional district from 1835 to 1839 and again from 1841 to 1843. He later served as a member of the Massachusetts General Court, first as a state Senator, and later a state representative. He also served as the third mayor of Fall River. His business career included interests textile mills, banking and railroads. He was the younger brother of noted land surveyor Simeon Borden.