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About: dbr:Ouabain     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatCardiacGlycosidesyago:WikicatMolecularFormulasyago:WikicatSteroidsyago:Abstraction100002137yago:Agent114778436yago:Alcohol107884567yago:Beverage107881800yago:BodySubstance105263850yago:CardiacGlycoside115059939yago:CausalAgent100007347yago:Chemical114806838yago:Communication100033020yago:Compound114818238yago:Drug103247620yago:DrugOfAbuse103248958yago:Fluid114939900yago:Food100021265yago:Formula106816935yago:Glycoside114887305yago:Hormone105407119yago:Liquid114940386yago:LiquidBodySubstance105397468yago:Material114580897yago:Matter100020827yago:Message106598915yago:MolecularFormula106817173yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Relation100031921yago:WikicatGlycosidesyago:WikicatHormonesdrugplantyago:Secretion105404728yago:Statement106722453yago:Steroid115057744yago:Substance100019613yago:Substance100020090yago:WikicatAlcoholsumbel-rc:DrugProduct New Facet based on Instances of this Class

Ouabain /wɑːˈbɑːɪn/ or /ˈwɑːbeɪn, ˈwæ-/ (from Somali waabaayo, "arrow poison" through French ouabaïo) also known as g-strophanthin, is a plant derived toxic substance that was traditionally used as an arrow poison in eastern Africa for both hunting and warfare. Ouabain is a cardiac glycoside and in lower doses, can be used medically to treat hypotension and some arrhythmias. It acts by inhibiting the Na/K-ATPase, also known as the sodium-potassium ion pump. However, adaptations to the alpha-subunit of the Na+/K+-ATPase via amino acid substitutions, have been observed in certain species, namely some herbivore- insect species, that have resulted in toxin resistance.