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Post-transfusion purpura (PTP) is a delayed adverse reaction to a blood transfusion or platelet transfusion that occurs when the body has produced alloantibodies to the allogeneic transfused platelets' antigens. These alloantibodies destroy the patient's platelets leading to thrombocytopenia, a rapid decline in platelet count. PTP usually presents 5–12 days after transfusion, and is a potentially fatal condition in rare cases. Approximately 85% of cases occur in women.

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  • Posttransfusionelle Purpura (de)
  • Porpora post-trasfusionale (it)
  • Post-transfusion purpura (en)
  • Małopłytkowość poprzetoczeniowa (pl)
  • Púrpura pós-transfusional (pt)
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  • Post-transfusion purpura (PTP) is a delayed adverse reaction to a blood transfusion or platelet transfusion that occurs when the body has produced alloantibodies to the allogeneic transfused platelets' antigens. These alloantibodies destroy the patient's platelets leading to thrombocytopenia, a rapid decline in platelet count. PTP usually presents 5–12 days after transfusion, and is a potentially fatal condition in rare cases. Approximately 85% of cases occur in women. (en)
  • La porpora post-trasfusionale è una reazione avversa alla trasfusione di eritrociti o piastrine concentrati, caratterizzata da una grave diatesi emorragica purpurea e mucosa conseguente a piastrinopenia, potenzialmente fatale, che insorge dopo 5-12 giorni dal trattamento. (it)
  • Małopłytkowość poprzetoczeniowa, plamica poprzetoczeniowa (ang. post-transfusion purpura, PTP) – skaza krwotoczna, pojawiająca się nagle, 5–15 dni po przetoczeniu krwi. Stanowi stan zagrożenia życia z powodu 10% ryzyka wystąpienia krwawień do OUN. (pl)
  • A púrpura pós-transfusional (PTP, em inglês: post-transfusion purpura) é uma reação adversa tardia a uma transfusão de sangue ou transfusão de plaquetas que ocorre quando o corpo produziu aloanticorpos para os antígenos de plaquetas transfundidos alogênicos. Esses aloanticorpos destroem as plaquetas do paciente, levando à trombocitopenia, um rápido declínio na contagem de plaquetas. A PTP geralmente se apresenta de 5 a 12 dias após a transfusão e é uma condição potencialmente fatal em casos raros. Cerca de 85% dos casos ocorrem em mulheres. (pt)
  • Die posttranfusionelle Purpura (eng. Post-transfusion purpura, PTP) ist eine verzögert auftretende, unerwünschte Transfusionsreaktion, die nach der Transfusion von zellulären Blutbestandteilen (z. B. Erythrozyten- oder Thrombozytenkonzentraten) auftreten kann. Ursächlich sind vom Empfänger des Blutprodukts gebildete gegen die Blutplättchen (Thrombozyten) gerichtete (antithrombozytäre) Alloantikörper, die neben den körperfremden (allogenen) ungewöhnlicherweise auch die körpereigenen (autologen) Thrombozyten zerstören. Die hieraus resultierende, bisweilen ausgeprägte Thrombozytopenie zeigt sich üblicherweise 5 bis 12 Tage nach der ursächlichen Transfusion und kann zu schweren Blutungen führen. Die PTP betrifft überwiegend Frauen, da diese durch vorangegangene Schwangerschaften entsprechende (de)
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  • Die posttranfusionelle Purpura (eng. Post-transfusion purpura, PTP) ist eine verzögert auftretende, unerwünschte Transfusionsreaktion, die nach der Transfusion von zellulären Blutbestandteilen (z. B. Erythrozyten- oder Thrombozytenkonzentraten) auftreten kann. Ursächlich sind vom Empfänger des Blutprodukts gebildete gegen die Blutplättchen (Thrombozyten) gerichtete (antithrombozytäre) Alloantikörper, die neben den körperfremden (allogenen) ungewöhnlicherweise auch die körpereigenen (autologen) Thrombozyten zerstören. Die hieraus resultierende, bisweilen ausgeprägte Thrombozytopenie zeigt sich üblicherweise 5 bis 12 Tage nach der ursächlichen Transfusion und kann zu schweren Blutungen führen. Die PTP betrifft überwiegend Frauen, da diese durch vorangegangene Schwangerschaften entsprechende Antikörper ausgebildet haben. (de)
  • Post-transfusion purpura (PTP) is a delayed adverse reaction to a blood transfusion or platelet transfusion that occurs when the body has produced alloantibodies to the allogeneic transfused platelets' antigens. These alloantibodies destroy the patient's platelets leading to thrombocytopenia, a rapid decline in platelet count. PTP usually presents 5–12 days after transfusion, and is a potentially fatal condition in rare cases. Approximately 85% of cases occur in women. (en)
  • La porpora post-trasfusionale è una reazione avversa alla trasfusione di eritrociti o piastrine concentrati, caratterizzata da una grave diatesi emorragica purpurea e mucosa conseguente a piastrinopenia, potenzialmente fatale, che insorge dopo 5-12 giorni dal trattamento. (it)
  • Małopłytkowość poprzetoczeniowa, plamica poprzetoczeniowa (ang. post-transfusion purpura, PTP) – skaza krwotoczna, pojawiająca się nagle, 5–15 dni po przetoczeniu krwi. Stanowi stan zagrożenia życia z powodu 10% ryzyka wystąpienia krwawień do OUN. (pl)
  • A púrpura pós-transfusional (PTP, em inglês: post-transfusion purpura) é uma reação adversa tardia a uma transfusão de sangue ou transfusão de plaquetas que ocorre quando o corpo produziu aloanticorpos para os antígenos de plaquetas transfundidos alogênicos. Esses aloanticorpos destroem as plaquetas do paciente, levando à trombocitopenia, um rápido declínio na contagem de plaquetas. A PTP geralmente se apresenta de 5 a 12 dias após a transfusão e é uma condição potencialmente fatal em casos raros. Cerca de 85% dos casos ocorrem em mulheres. (pt)
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