Psilocybe oaxacana is a species of psychedelic mushroom in the family Hymenogastraceae native to Oaxaca, Mexico. It is in the Psilocybe fagicola complex with Psilocybe fagicola, Psilocybe banderillensis, Psilocybe columbiana, Psilocybe herrerae, Psilocybe keralensis, Psilocybe neoxalapensis, and .