Rotavirus vaccine is a vaccine used to protect against rotavirus infections, which are the leading cause of severe diarrhea among young children. The vaccines prevent 15–34% of severe diarrhea in the developing world and 37–96% of severe the risk of death among young children due to diarrhea. Immunizing babies decreases rates of disease among older people and those who have not been immunized. The vaccines are safe. This includes their use in people with HIV/AIDS. The vaccines are made from weakened rotavirus.