The siege of Plei Me (Vietnamese: Bao vây Plei Me; 19–25 October 1965) was the beginning phase of the first major confrontation between soldiers of the North Vietnamese People's Army of Vietnam (PAVN) and the U.S. Army during the Vietnam War. The lifting of the siege by South Vietnamese forces and American air power was followed by the pursuit of the retreating North Vietnamese from 28 October until 12 November, setting the stage for the Battle of Ia Drang.