Tando Muhammad Khan (Sindhi: ٽنڊو محمد خان; Urdu: ٹنڈو محمد خان) is a city and headquarter of the Tando Muhammad Khan District located in Sindh, Pakistan. Is is named after Mir Muhammad Khan Talpur Shahwani. It is the 95th largest city of Pakistan, according to 2017 census. It has a railway station on the Badin–Hyderabad Branch Line.