William Lofland Dudley (April 16, 1859 – September 8, 1914) was an American chemistry professor at both the University of Cincinnati and Vanderbilt University and an athletics pioneer during the Progressive Era. At Vanderbilt, he was appointed dean of its medical department. He was also once vice-president of the American Association for the Advancement of Science, and was notably director of affairs on the Tennessee Centennial Exposition executive committee.