About: Μ-opioid receptor     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Unit109465459, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)
QRcode icon
http://dbpedia.demo.openlinksw.com/c/3pGqXd2f24

The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins. They are also referred to as μ(mu)-opioid peptide (MOP) receptors. The prototypical μ-opioid receptor agonist is morphine, the primary psychoactive alkaloid in opium and for which the receptor was named, with mu being the Greek letter m. It is an inhibitory G-protein coupled receptor that activates the Gi alpha subunit, inhibiting adenylate cyclase activity, lowering cAMP levels.

AttributesValues
rdf:type
rdfs:label
  • Μ opioidní receptor (cs)
  • Receptor opioide mu (es)
  • Recettori μ-oppioidi (it)
  • Μ-opioid receptor (en)
  • OPRM1 (uk)
rdfs:comment
  • μ opioidní receptory, čti mjů ( MOR ) jsou třídou opioidních receptorů s vysokou afinitou pro enkefaliny a beta-endorfin a nízkou k dynorfinům. Proto jsou oba označovány také za μ opioidní peptidové (MOP) receptory. Prototypem agonisty μ opioidního receptoru je morfin jako primární psychoaktivní alkaloid v opiu. Jde o inhibiční receptor spřažený s G-proteinem, který aktivuje alfa podjednotku G I, inhibici aktivity adenylátcyklázy a snižující hladinu cAMP. (cs)
  • El receptor opioide mu o receptor opiode μ es un receptor opioide localizado principalmente en el cerebro y la médula espinal. Tiene importantes implicaciones en la analgesia y los efectos psicoactivos de todos los opioides. Es activado por los opioides como la morfina, el prototípico, aunque tiene alta afinidad por la encefalina. Existen tres tipos de receptores opioides mu (μ): μ1, μ2 y μ3. (es)
  • I recettori μ-oppioidi (recettori oppioidi mu, o MOR) sono una classe di recettori degli oppioidi con un'alta affinità per encefaline e beta-endorfina, ma una bassa affinità per dinorfine. Essi sono anche denominati peptidi (MOP) recettori μ-oppioidi. La morfina, alcaloide psicoattivo principale contenuto nell'oppio, è l'agonista prototipico in grado di attivare i recettori μ. (it)
  • The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins. They are also referred to as μ(mu)-opioid peptide (MOP) receptors. The prototypical μ-opioid receptor agonist is morphine, the primary psychoactive alkaloid in opium and for which the receptor was named, with mu being the Greek letter m. It is an inhibitory G-protein coupled receptor that activates the Gi alpha subunit, inhibiting adenylate cyclase activity, lowering cAMP levels. (en)
  • OPRM1 (англ. Opioid receptor mu 1) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 6-ї хромосоми. Довжина поліпептидного ланцюга білка становить 400 амінокислот, а молекулярна маса — 44 779. Послідовність амінокислот A: АланінC: ЦистеїнD: Аспарагінова кислотаE: Глутамінова кислотаF: ФенілаланінG: ГліцинH: ГістидинI: ІзолейцинK: ЛізинL: ЛейцинM: МетіонінN: АспарагінP: ПролінQ: ГлутамінR: АргінінS: СеринT: ТреонінV: ВалінW: Триптофан Y: Тирозин (uk)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Mu-opioid_receptor.png
dct:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
Faceted Search & Find service v1.17_git147 as of Sep 06 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 08.03.3331 as of Sep 2 2024, on Linux (x86_64-generic-linux-glibc212), Single-Server Edition (378 GB total memory, 65 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software