The 1941 Missouri Tigers football team was an American football team that represented the University of Missouri in the Big Six Conference (Big 6) during the 1941 college football season. The team compiled an 8–2 record (5–0 against Big 6 opponents), won the Big 6 championship, lost to Fordham in the 1942 Sugar Bowl, outscored all opponents by a combined total of 226 to 39, and was ranked No. 7 in the final AP Poll. Don Faurot was the head coach for the seventh of 19 seasons. The team played its home games at Memorial Stadium in Columbia, Missouri.